Green beauty and Clean beauty are becoming more and more popular in the market. Consumers’ awareness of skin care is awakened, skin care concepts have changed, and attention to minimalist skin care and natural ingredients products is increasing day by day. Under this trend, Chinese herbal medicines and plant extracts have come to the forefront, and there are many research results on anti-wrinkle Chinese herbal medicines and plant extracts. Let’s take a look at the plant extracts with high click-through rate and high likes. Come on, old folks, after you have dried this bowl of plant extract soup, you can increase your knowledge tomorrow! Before picking up anti-wrinkle plant extracts, let’s review the main “culprits” of wrinkles: excessive free radicals, overexpression of matrix metalloproteinases (MMPs), and decreased collagen synthesis. Then you have to prescribe the right medicine for anti-wrinkle, and work hard on these points. The first appearance is Centella asiatica extractThe self-introduction of Centella asiatica extract is also very proud. Its weapon arsenal contains flavonoids, triterpene saponins, etc. A variety of chemicals, such as asiatic acid, madecassoside, madecassoside. Among them, Centella asiatica can stimulate the proliferation of fibroblasts, activate the TGF-β1/Smad signal transduction pathway, and can also significantly increase the content of collagen and cellular fibronectin [1]; The flavonoids in Centella asiatica have a strong antioxidant effect, which can remove excessive free radicals in the body [2]; in addition, asiaticoside [3] and asiatic acid [4] can reduce cellular inflammation. produce. Take a look, the effect of Centella asiatica extract on the skin is three-dimensional and comprehensive, and it is also very handy in anti-wrinkle. “He is mad at him, and I am quite able to carry it.” Before seeing it, first heard the sound, the Echinacea purpurea extract came with his nuclear weapons. The main functions of Echinacea purpurea extract in cosmetics and skin care products are antioxidants, anti-inflammatory agents and moisturizers. It can eliminate free radicals, has antioxidant properties, and can alleviate aging [5]. According to Estee Lauder related Phenibut on sale patents, the extract of Echinacea purpurea is rich in cichoric acid, which targets the circadian rhythm gene per1 gene (this gene can maintain the body’s normal circadian rhythm and avoid rhythm disorders. The various body problems caused by its role are shown in the figure below), and it has a good effect of activating the circadian rhythm gene per1 [6] (this skill is powerful, and it can be accurately guided to solve the problem from the root). It can also stimulate cell activity, enhance the repairing power of the skin itself, and repair the barrier. Studies have also shown that Echinacea purpurea extract has anti-inflammatory and anti-allergic effects [7]. Plant extracts are really “eighteen martial arts, each showing their magical powers”, kelp extract is a “straight boy”, although there is no romantic sentiment, but it is not long-winded, and it is done. Kelp extract can directly inhibit the activity of elastase, which is a destructive molecule that can destroy elastin and other proteins. Kelp extract also has the effect of scavenging oxygen free radicals, exerting anti-wrinkle and anti-aging effects. Kelp extract contains active substances such as fucoxanthin and kelp polysaccharide. Fucoxanthin [8] as an oxygen free radical scavenger can protect the skin from excessive oxidation of oxygen free radicals, prevent lipid peroxidation, and have the functions of freckle, wrinkle prevention and anti-aging. In addition, kelp polysaccharide [9] also has an obvious scavenging effect on free radicals (and shows a dose-effect relationship), thereby delaying skin aging and producing wrinkles. There is also a “straight boy”-Xia Xue Pian lotus bulb extract. This is a natural water-soluble plant extract extracted from the dormant Xia Xuepi lotus bulbs, which can increase the expression of SOD (superoxide dismutase) and exert anti-oxidation and slow down The effect of aging; it can also inhibit the contraction of the muscles in the neuromuscular, and can be used as an “effective botulinum toxin substitute”. This skill can prevent wrinkles from the root cause. In addition, Xia Xuepi lotus bulb extract can also stimul Phenibut powder wholesale ate the production of collagen and elastin, and play a timely replenishment effect. Coupled with its good oxidation resistance, it is at ease for anti-aging and anti-wrinkle. There are also some data on related products. The water-soluble IBR-Snowflake? of Xia Xuepilian bulb extract reduces the number of fine lines by 30% and the number of deep lines by 15% within 28 days. Okay, the previous introductions are all relatively unfamiliar to everyone, and then I will introduce the two most familiar “strangers”, one is wheat germ extract, the other is pomegranate extract (pomegranate fruit and pomegranate peel ). The first time I met, goodbye is “looking for him a thousand times in the crowd, suddenly looking back, but the person is in the light of the lights.” Wheat germ extract contains fatty oil, natural vitamin E and other ingredients, which has a good effect on the proliferation of fibroblasts, and can activate skin and anti-aging; it has an inhibitory effect on collagenase and delays collagen Decomposition of proteins and other proteins; also has strong antioxidant capacity, can scavenge DPPH free radicals, hydroxyl free radicals, etc. [10], avoid excessive free radicals to activate the activity of matrix metalloproteinases (MMPs), thereby inhibiting and delaying wrinkles . Pomegranate is rich in active substances such as ellagic acid, gallic acid, anthocyanin, and a variety of amino acids. It has strong antioxidant, anti-inflammatory and free radical scavenging abilities, and can prevent UVA and UVB induced Skin damage prevents the occurrence of photoaging. In addition, studies have shown that pomegranate fruit extract can inhibit collagenase, and pomegranate peel extract can scavenge DPPH free radicals[11]; the combination of pomegranate seed oil and pomegranate peel extract can promote collagen synthesis and inhibit matrix metalloproteinase activity , Promote the proliferation of keratinocytes, promote skin growth and delay wrinkles. The above content mainly introduces several anti-wrinkle plant extracts that have attracted more attention and have more research results. It can be seen Buy Phenibut Online that their anti-wrinkle effects are also different, but regardless of black cats and white cats , A good cat can catch a mouse. In addition, the anti-wrinkle effects of plant extracts are more through antioxidant pathways, such as Mimosa gracilis bark extract, sweet tea extract, comfrey root extract, alfalfa extract, milk thistle extract I will not introduce too much here. [1]Chen Li,Wang Tingting et al. Effects of asiaticoside on the intervention of rabbit ear wound repair at different stages and the immunohistochemical expression of transforming growth factor β1 and Smad3[J].Hebei Journal of Traditional Chinese Medicine, 2019, 41(10):1532-1535.[2] He Huijuan, Li Jing, Zhu Weijie, etc. Study on the antioxidant and immunomodulatory effects of Centella asiatica extract[J]. Chinese Journal of Pathophysiology, 2010 ,26(4):771-776.[3] Liu Tao et al. Effects of asiaticoside on the proliferation of alveolar epithelial cells and Vimentin protein expression induced by TGF-β1[J]. Chinese Journal of Immunology ,2019,35(1):25-29.[4] Hao C, Hua XM, Ze BC, et a1. The anti-inflammatory effects of asiatic acid in lipopolysaccha ride-stimulated human corneal epithelial cells[J]. Int J Ophthalmol-Chi, 2017, 10(2):179-185. [5] Gao Yanni, Yuan Ying, Wang Jilei et al. Effects of Echinacea purpurea extract on the antioxidant performance of broiler chicken serum[J]. Animal Nutrition and Feed Science, 2008,35(6 ):18-21.[6] Xing Chen, Song Lun, The regulation system for the generation and maintenance of circadian rhythm[J]. Military Medicine,2017,41(8):698-702.[6] p>[7] Wang Shunxiang, Wei Jingjian, Wang Yipeng. The anti-tumor effect of purple echinacea on tumor-bearing mice and the effect of tumor necrosis factor production[J]. Carcinogenesis·Aberration·Mutation,2002.2. [8]Kim KN, Heo SJ, Yoon WJ, et al. Fucoxanthin inhibits the inflammatory response by suppressing the activation of NF-κBand MAPKs in lipopolysaccharide-induced RAW264.7 macrophages[J].European Journal of Pharmacology, 2010 , 649(1-3): 369-375.[9]Ha AW,Na SJ,Kim WK. Antioxidant effects of fucoxanthin rich powder in rats fed with high fat diet[J].Nutrition Research and Practice, 2013, 7(6):475-80.[10]Chen Weijun, Cao Wei. Study on the antioxidant activity of wheat germ extract[J]. Food Science,2004,25(10) :294-300.[11] Wang Jianxin. Encyclopedia of cosmetic plant raw materials[M]. China Textile Publishing House, 2012.6.